The purpose of this study was to investigate the influences of the contents of AIDS education on attitudes toward people with AIDS (PWA). One hundred and eighty-four college students responded to a questionnaire that measured (1) four types of AIDS education as independent variables (prevention against infection, the route of infection, the present state of AIDS, and living together with PWA), (2) cognitive response (amount of knowledge about the route of infection) and affective response (intensity of fear toward AIDS) as mediating variables, (3) four types of attitudes toward PWA as dependent variables (image toward PWA, resisting contact with PWA, attitude towards interactive behavior with PWA, and evaluative attitude toward PWA). Three independent variables had no effect on either of the two mediating variables. However, education about living with PWA had a significant positive effect on the knowledge about route of infection. Also that knowledge had a significant negative effect on resisting contact with PWA. Surprisingly, the intensity of fear toward AIDS showed a significant positive effect on resisting contact with PWA, and significant negative effects on the remaining three types of attitude toward PWA.