This study aims to clarify the structure of the process and issues surrounding career guidance for students with developmental disorders, who are learning through a high school equivalent curriculum at upper secondary divisions of special schools for students with health impairments. Semi-structured interviews involving seven teachers from upper secondary divisions of special schools were conducted to collect data for qualitative data analysis. Consequently, three categories of issues that affect students’ career decisions were identified: student issues, school system issues, and family and social resources issues. In addition, three categories for practices were generated: guidance policies, guidance and support for realizing their career paths, and building and maintaining connections with local communities. One category for achievement points after graduation was also generated: career paths of upper secondary divisions graduates. Based on these results, this study concluded that the characteristic issues are effects of school refusal, maladaptation on career learning, and the narrowing of career choices due to lack of support from family. Moreover, maintaining a receptive approach and connections that were established during school also identified as characteristic practices.