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Hiroshima Journal of Medical Sciences Volume 33 Issue 4
published_at 1984-12

Experience with the Use of Mizoribine in Human Renal Transplantation

Mizoribine を用いたヒト腎移植の経験
Dohi Kiyohiko
Yahata Hiroshi
Fukuda Yasuhiko
Takenaka Masaharu
Tabe Yasuji
Ono Eiji
Fukuda Makoto
Omotehara Tamon
Eto Takaaki
Ezaki Haruo
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HiroshimaJMedSci_33_809.pdf
Abstract
In addition to steroids and azathioprine, mizoribine was administered to 17 renal transplant recipients. In 9 of the 17, 16 acute rejections occurred. Seven of these 9 recovered without deterioration of graft function, but one lost the function. Mizoribine, which has been elucidated to produce a chronic rejection preventing effect fully when administered concurrently with steroids and azathioprine, proved to give a satisfactory immunosuppressive effect in a dose of 1 mg/kg/day when used simaltaneously with steroids and azathioprine.
About This Article
Keywords
Renal transplantation
Mizoribine
Rejection
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