Hiroshima Journal of Medical Sciences Volume 33 Issue 2
published_at 1984-06

Studies of Alloantibody Effect on Skin Graft Survival in Mice

alloantibody のマウス skin graft survival に及ぼす影響
Dohi Kiyohiko
Asahara Toshimasa
Ono Eiji
Yahata Hiroshi
Fukuda Yasuhiko
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HiroshimaJMedSci_33_271.pdf
Abstract
Alloantisera (anti-donor and anti-recipient alloantiserum) were prepared by skin grafting followed four inoculations of 1×10^7 splenocytes.

These alloantisera were cytotoxic (×64) to target cells specifically.

Anti-recipient alloantiserum was effective on enhancing skin graft survival in mice as same as anti-donor alloantiserum, when administered on the operative day, second postoperative day and fourth postoperative day between 50-200 μl at one time.
Keywords
Alloantibody
Immunosuppression
Mouse