Hiroshima Journal of Medical Sciences 33 巻 2 号
1984-06 発行

The Serum Pregnancy Associated α2-Glycoprotein Level in Patients with IgA Nephropathy

IgA腎症患者における血清 Pregnancy associated α2-glycoprotein
Toi Shunji
Hamaguchi Naoki
Wada Koji
Toyota Toshihide
Hayashi Kanoko
Arita Michiko
Usui Koji
Tada Misaki
Yorioka Noriaki
Yamakido Michio
Nishimoto Yukio
Hata Jyotaro
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HiroshimaJMedSci_33_131.pdf
Abstract
Serum pregnancy associated α2-glycoprotein levels in 51 IgA nephropathy patients (28 males and 23 females) and 46 healthy subjects (31 males and 15 females) were determined by enzyme-immunoassay. The results showed the serum pregnancy associated α2-glycoprotein levels to be significantly increased in the IgA nephropathy patients over the healthy subjects in both sexes (males: p<0.01, females: p<0.001). Further, in the male patients, the level was significantly increased in those with proteinuria, also there was a significant negative correlation between the concentration and PSP 15 minute value and GFR. On the other hand, in the female patient group there was a significant positive correlation between serum total cholesterol level.

On the basis of these findings, we presume that the determination of serum pregnancy associated α2-glycoprotein level may be useful in assuming the prognosis of IgA nephropathy.
著者キーワード
Pregnancy associated α2-glycoprotein
IgA nephropathy