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Hiroshima Journal of Medical Sciences 33 巻 2 号
1984-06 発行

VIPergic Innervation of the Gall Bladder in Health and Disease

胆のう疾患のVIP神経
Kishimoto Shinya
Okamoto Kazuma
Shimizu Satoru
Kambara Akihiko
Kawanishi Masahiro
Yamamoto Masahiro
Iwasaki Yukiyoshi
Kajiyama Goro
Miyoshi Akima
Yanaihara Noboru
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Abstract
The immunocytochemical distribution of vasoactive intestinal peptide (VIP) was studied in healthy and diseased regions of the human gall bladder wall obtained after operation for cholelithiasis. Ganglionated plexuses containing VIP-like immunoreactive nerves and fibers were located in the subepithelial and muscle layer of the normal region, suggesting that VIP may exert gall bladder function, while such ganglionated plexuses were almost absent, being replaced by inflammatory cells and fibrotic tissue. This suggests that the lack of VIP may be one of the causes in the pathogenesis of gall bladder dysfunction in the case of cholelithiasis associated chronic cholecystitis.
About This Article
著者キーワード
VIP
Nerves
Gall bladder
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