Deaf-blind individuals are usually treated at welfare offices and medical institutions as ones having two separate disabilities. However, it is necessary to support them considering visual and hearing impairments as a combined disability to improve their quality of life. In this study, the author has tried to provide comprehensive supports based on patients' complains and/or inconvenience. Nine deaf-blind patients were supported by the conventional approach, resulting in incomplete achievement for their requirements. In contrast, the comprehensive approach succeeded in enhancing of the quality of life in five deaf-blind patients. These results suggest that the comprehensive supporting system may play an important role in improving the quality of life in individuals with multiple handicaps.