Hiroshima Journal of Medical Sciences Volume 34 Issue 1
published_at 1985-03

Distribution and Endocrine Morphology of Polypeptide YY (PYY) Containing Cells in the Human Gut

KISHIMOTO Shinya
KATO Reiko
MUKAI Toshikazu
KANBARA Akihiko
OKAMOTO Kazuma
SHIMIZU Satoru
DAITOKU Kunihiko
KAJIYAMA Goro
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HiroshimaJMedSci_34_155.pdf
Abstract
Using human materials, the distribution of PYY containing cells was determined by immunocytochemical methods and discussion was made on their morphological endocrinology. PYY cells were fairly numerous in the lower gastrointestinal tract of man, particularly in the colon and rectum. The cells were also present in the pancreas and duodenum but quite rarely. PYY cells were not observed at all in the lower part of the esophagus, stomach and gall bladder. Their peculiar and characteristic shapes as well as distribution suggest that PYY may have some action (probably specific) on the function of the distal gastrointestinal tract.
Keywords
Gastrointestinal tract
PYY