Hiroshima Journal of Medical Sciences 32 巻 3 号
1983-09 発行

Chromosomal Abnormalities in Severely Malnourished Indian Children

インドにおける重症栄養失調児の染色体異常
Murthy P. Balakrishna
Rahiman M. Abdul
全文
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HiroshimaJMedSci_32_291.pdf
Abstract
The frequencies of chromosomal aberrations in Giemsa-banded preparations obtained from peripheral blood cultures of 5 kwashiorkor, 3 marasmic and 2 marasmic-kwashiorkor patients were investigated. Analysis of 1120 metaphases from these patients revealed an aberration rate of 5.80 per cent as against a frequency of 1.66 per cent seen in control children. However, no particular chromosome or chromosome group seems to be more affected in malnourished children. Furthermore, malnourished children with associated infections were observed to exhibit more number aberrations than those without infections. These observations thus, support the suggestion that malnourished children exhibit increased frequencies of chromosomal damage.
著者キーワード
PEM
Malnutrition
Chromosomes