Chromosomal Abnormalities in Severely Malnourished Indian Children

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Title ( eng )
Chromosomal Abnormalities in Severely Malnourished Indian Children
Title ( jpn )
インドにおける重症栄養失調児の染色体異常
Creator
Murthy P. Balakrishna
Rahiman M. Abdul
Source Title
Hiroshima Journal of Medical Sciences
Volume 32
Issue 3
Start Page 291
End Page 294
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
The frequencies of chromosomal aberrations in Giemsa-banded preparations obtained from peripheral blood cultures of 5 kwashiorkor, 3 marasmic and 2 marasmic-kwashiorkor patients were investigated. Analysis of 1120 metaphases from these patients revealed an aberration rate of 5.80 per cent as against a frequency of 1.66 per cent seen in control children. However, no particular chromosome or chromosome group seems to be more affected in malnourished children. Furthermore, malnourished children with associated infections were observed to exhibit more number aberrations than those without infections. These observations thus, support the suggestion that malnourished children exhibit increased frequencies of chromosomal damage.
Keywords
PEM
Malnutrition
Chromosomes
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University School of Medicine
Date of Issued 1983-09
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6417064