Hiroshima Journal of Medical Sciences 30 巻 2 号
1981-06-10 発行

NATURAL KILLER (NK) ACTIVITY IN PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE

慢性肉芽腫症患者のナチュラル・キラー(NK)活性について
Tanaka Yoshito
Sakano Takashi
Usui Tomofusa
全文
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HiroshimaJMedSci_30_135.pdf
Abstract
Natural killer (NK) activity against K 562 target cells was explored in 4 patients with chronic granulomatous disease (CGD). Although the NK activity of these patients was normal, the activity did not change after removal of monocytes from the effector cell population, contrary to normal adult controls.  

The possibility of a defect in the regulatory function of monocytes on NK activity in CGD patients is discussed.
内容記述
This work was supported by a Research Grant (No. 544050) from the Ministry of Education, Science and Culture of Japan.