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Hiroshima Journal of Medical Sciences Volume 30 Issue 2
published_at 1981-06-10
NATURAL KILLER (NK) ACTIVITY IN PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE
慢性肉芽腫症患者のナチュラル・キラー(NK)活性について
Tanaka Yoshito
Sakano Takashi
Usui Tomofusa
Abstract
Natural killer (NK) activity against K 562 target cells was explored in 4 patients with chronic granulomatous disease (CGD). Although the NK activity of these patients was normal, the activity did not change after removal of monocytes from the effector cell population, contrary to normal adult controls.
The possibility of a defect in the regulatory function of monocytes on NK activity in CGD patients is discussed.
The possibility of a defect in the regulatory function of monocytes on NK activity in CGD patients is discussed.
About This Article
Descriptions
This work was supported by a Research Grant (No. 544050) from the Ministry of Education, Science and Culture of Japan.
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