この文献の参照には次のURLをご利用ください : https://ir.lib.hiroshima-u.ac.jp/00037372
Hiroshima Journal of Medical Sciences 30 巻 2 号
1981-06-10 発行
EFFECT OF NEURAMINIDASE ON THE DURATION OF CONTACT WITH CON A IN LYMPHOCYTE STIMULATION
リンパ球活性化におけるコンカナバリンAの接触時間に対するノイラミニダーゼの作用
Sakano Takashi
Kittaka Eishi
Hyodo Sumio
Horino Nobuko
Tanaka Yoshito
Usui Tomofusa
Abstract
Neuraminidase-treatment greatly increased 3H-thymidine incorporation by human lymphocytes at lower concentrations of Con A. An irreversible sequence after 24 hr of incubation in the presence of the optimal concentration of Con A was found. However, at a suboptimal concantraiton of Con A, neuraminidase-treated lymphocytes exposed to Con A for 72 hr exhibited a greater magnitude of 3H-thymidine incorporation in contrast to the neuraminidase-treated lymphocytes exposed to Con A for 24 hr, indicating that the enancement effect of neuraminidase was not due to the increased binding of Con A to cell surfaces.
About This Article
内容記述
This work was supported in part by Grant-in-Aid for Scientific Research (Project Nos. 544050 and 577401) from the Ministry of Education, Science and Culture of Japan.
Other Article
PP. 47 - 54
PP. 55 - 59
PP. 85 - 92
PP. 115 - 126