この文献の参照には次のURLをご利用ください : https://ir.lib.hiroshima-u.ac.jp/00037835
Hiroshima Journal of Medical Sciences 45 巻 1 号
1996-03 発行
The Protective Effect of Low Power He-Ne Laser Against Erythrocytic Damage Caused by Artificial Heart-Lung Machines
Abstract
We studied the protective effects of low power He-Ne laser irradiation on erythrocytes against the damage caused by experimental artificial heart-lung machines.
The erythrocyte suspension in a closed circuit was perfused with a roller pump. One of two circuits was used for laser treatment and the other for control. The laser group demonstrated significantly higher erythrocyte deformability and erythrocyte ATP levels, and lower free hemoglobin and lipid peroxide levels. A laser output power of 8.5 mW was most effective in protecting the erythrocytes. A further morphological finding using a scanning electron microscope showed fewer echinocytes and more discocytes in the laser group. This finding was consistent with the results of physiological and biochemical tests.
Low power He-Ne laser irradiation was shown to protect human erythrocytes from the damage caused by an experimental artificial heart-lung machine, raising the possibility of the clinical application of low power He-Ne laser treatment during extracorporeal circulation in cardiovascular surgery.
The erythrocyte suspension in a closed circuit was perfused with a roller pump. One of two circuits was used for laser treatment and the other for control. The laser group demonstrated significantly higher erythrocyte deformability and erythrocyte ATP levels, and lower free hemoglobin and lipid peroxide levels. A laser output power of 8.5 mW was most effective in protecting the erythrocytes. A further morphological finding using a scanning electron microscope showed fewer echinocytes and more discocytes in the laser group. This finding was consistent with the results of physiological and biochemical tests.
Low power He-Ne laser irradiation was shown to protect human erythrocytes from the damage caused by an experimental artificial heart-lung machine, raising the possibility of the clinical application of low power He-Ne laser treatment during extracorporeal circulation in cardiovascular surgery.
About This Article
内容記述
This study was presented at the 6th Japan Laser Therapy Association, held on June 25-26, 1994 in Kobe, at the 32d Japanese Society for Artificial Organs, held on October 12-13, 1994 in Tokyo, at the 47th Japanese Association for Thoracic Surgery, held on October 25-27, 1994 in Chiba, at the 95th Japan Surgical Society, held on April 10-12, 1995 in Nagoya, and at the 33d Japanese Society for Artificial Organs, held on November 7-9, 1995 in Osaka.
著者キーワード
Artificial heart-lung machine
Low power He-Ne laser
Erythrocyte deformability
Free hemoglobin
Other Article
PP. 23 - 30