The Protective Effect of Low Power He-Ne Laser Against Erythrocytic Damage Caused by Artificial Heart-Lung Machines
Hiroshima Journal of Medical Sciences 45 巻 1 号
15-22 頁
1996-03 発行
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| ファイル情報(添付) | |
| タイトル ( eng ) |
The Protective Effect of Low Power He-Ne Laser Against Erythrocytic Damage Caused by Artificial Heart-Lung Machines
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| 作成者 |
Takashi Itoh
Murakami Hironobu
Orihashi Kazumasa
Matsuura Yuichiro
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| 収録物名 |
Hiroshima Journal of Medical Sciences
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| 巻 | 45 |
| 号 | 1 |
| 開始ページ | 15 |
| 終了ページ | 22 |
| 収録物識別子 |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| 抄録 |
We studied the protective effects of low power He-Ne laser irradiation on erythrocytes against the damage caused by experimental artificial heart-lung machines.
The erythrocyte suspension in a closed circuit was perfused with a roller pump. One of two circuits was used for laser treatment and the other for control. The laser group demonstrated significantly higher erythrocyte deformability and erythrocyte ATP levels, and lower free hemoglobin and lipid peroxide levels. A laser output power of 8.5 mW was most effective in protecting the erythrocytes. A further morphological finding using a scanning electron microscope showed fewer echinocytes and more discocytes in the laser group. This finding was consistent with the results of physiological and biochemical tests. Low power He-Ne laser irradiation was shown to protect human erythrocytes from the damage caused by an experimental artificial heart-lung machine, raising the possibility of the clinical application of low power He-Ne laser treatment during extracorporeal circulation in cardiovascular surgery. |
| 著者キーワード |
Artificial heart-lung machine
Low power He-Ne laser
Erythrocyte deformability
Free hemoglobin
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| 内容記述 |
This study was presented at the 6th Japan Laser Therapy Association, held on June 25-26, 1994 in Kobe, at the 32d Japanese Society for Artificial Organs, held on October 12-13, 1994 in Tokyo, at the 47th Japanese Association for Thoracic Surgery, held on October 25-27, 1994 in Chiba, at the 95th Japan Surgical Society, held on April 10-12, 1995 in Nagoya, and at the 33d Japanese Society for Artificial Organs, held on November 7-9, 1995 in Osaka.
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| NDC分類 |
医学 [ 490 ]
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| 言語 |
英語
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| 資源タイプ | 紀要論文 |
| 出版者 |
Hiroshima University Medical Press
|
| 発行日 | 1996-03 |
| 出版タイプ | Version of Record（出版社版。早期公開を含む） |
| アクセス権 | オープンアクセス |
| 収録物識別子 |
[ISSN] 0018-2052
[NCID] AA00664312
|
