The results of the liver functional tests in 45 cases of liver cirrhosis (LC) and 29 cases of chronic hepatitis (CH) confirmed by liver biopsy during operation were compared and studied. It was recognized that there were significant differences of albumin (p < 0.05), prothrombin time (p < 0.01), cholinesterase (p < 0.01) and KICG (p < 0.05) between LC and CH. The rate of hospital death in LC group proved to higher that that in CH group. Therefore, in the cases where LC is diagnosed before or during operation and the decrease in the above four parameters were low, careful consideration for the selection of surgical formulas and post-operative treatment are required.