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Hiroshima Journal of Medical Sciences 35 巻 4 号
1986-12 発行

Antral Somatostatin Contents and Acidity of Gastric Juice in Normal Subjects and Patients with Duodenal Ulcer

SUMII Koji
SUMIOKA Masaaki
HIRATA Ken
UEMURA Naomi
TARI Akira
YOSHIHARA Masaharu
SEKITO Masaki
TOKUTOMI Tadashi
INABA Yoshirou
TESHIMA Hitoshi
INBE Akira
TOKUMO Kenji
OHGOSHI Hiroaki
HARUMA Ken
KAJIYAMA Goro
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HiroshimaJMedSci_35_343.pdf
Abstract
The antral somatostatin contents were investigated in biopsy specimens of the antrum from normal subjects and patients with duodenal ulcer. There was good correlation (r=0.77044) between antral somatostatin contents and maximal acidity in normal subjects, but the correlation between antral somatostatin contents and maximal acid output was not significant (r=0.254367). This result may indicate that antral somatostatin content is regulated by intragastric pH in normal subjects. On the other hands, no correlation was observed between antral somatostatin contents and acidity or acid output in patients with duodenal ulcer.
Therefore the impaired regulation of acid on antral somatostatin contents could be one of the important factors in the pathogenesis of duodenal ulcer disease.
About This Article
著者キーワード
Duodenal Ulcer
Antral somatostatin
Acidity
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