Antral Somatostatin Contents and Acidity of Gastric Juice in Normal Subjects and Patients with Duodenal Ulcer

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タイトル ( eng )
Antral Somatostatin Contents and Acidity of Gastric Juice in Normal Subjects and Patients with Duodenal Ulcer
作成者
SUMII Koji
SUMIOKA Masaaki
HIRATA Ken
UEMURA Naomi
TARI Akira
YOSHIHARA Masaharu
SEKITO Masaki
TOKUTOMI Tadashi
INABA Yoshirou
TESHIMA Hitoshi
INBE Akira
TOKUMO Kenji
OHGOSHI Hiroaki
HARUMA Ken
KAJIYAMA Goro
収録物名
Hiroshima Journal of Medical Sciences
35
4
開始ページ 343
終了ページ 346
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
The antral somatostatin contents were investigated in biopsy specimens of the antrum from normal subjects and patients with duodenal ulcer. There was good correlation (r=0.77044) between antral somatostatin contents and maximal acidity in normal subjects, but the correlation between antral somatostatin contents and maximal acid output was not significant (r=0.254367). This result may indicate that antral somatostatin content is regulated by intragastric pH in normal subjects. On the other hands, no correlation was observed between antral somatostatin contents and acidity or acid output in patients with duodenal ulcer.
Therefore the impaired regulation of acid on antral somatostatin contents could be one of the important factors in the pathogenesis of duodenal ulcer disease.
著者キーワード
Duodenal Ulcer
Antral somatostatin
Acidity
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1986-12
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 2883159