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Hiroshima Journal of Medical Sciences 32 巻 1 号
1983-03 発行

Natural Killer Activity of Normal Human Peripheral Blood Lymphocytes : I. Inhibitory effect of ammonium chloride solution

正常ヒト未梢血リンパ球のナチュラル・キラー活性について : I. アンモニウムクロライドによる活性抑制機序の検討
Kittaka Eishi
Hyodo Sumio
Kawaguchi Yoshinori
Suzawa Toshifumi
Tanaka Yoshito
Sakano Takashi
Usui Tomofusa
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HiroshimaJMedSci_32_83.pdf
Abstract
The inhibitory effect of ammonium choride pretreatment of human peripheral blood lymphocytes on natural killer (NK) activity to myeloid leukemic cell line K-562 was studied. The more dilute the ammonium chloride solution, the less was the inhibitory effect on NK activity. This inhibitory effect was weaker when effector cells were treated at 4°C than at 37°C. Inhibited NK activity recovered partially after incubation for 24 hours.
About This Article
内容記述
This work was supported by a Research Grant (No. 544050) from the Ministry of Education, Science and Culture of Japan.
著者キーワード
Natural killer activity
Ammonium chloride solution
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