Natural Killer Activity of Normal Human Peripheral Blood Lymphocytes : I. Inhibitory effect of ammonium chloride solution

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Title ( eng )
Natural Killer Activity of Normal Human Peripheral Blood Lymphocytes : I. Inhibitory effect of ammonium chloride solution
Title ( jpn )
正常ヒト未梢血リンパ球のナチュラル・キラー活性について : I. アンモニウムクロライドによる活性抑制機序の検討
Creator
Kittaka Eishi
Hyodo Sumio
Kawaguchi Yoshinori
Suzawa Toshifumi
Tanaka Yoshito
Sakano Takashi
Usui Tomofusa
Source Title
Hiroshima Journal of Medical Sciences
Volume 32
Issue 1
Start Page 83
End Page 86
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
The inhibitory effect of ammonium choride pretreatment of human peripheral blood lymphocytes on natural killer (NK) activity to myeloid leukemic cell line K-562 was studied. The more dilute the ammonium chloride solution, the less was the inhibitory effect on NK activity. This inhibitory effect was weaker when effector cells were treated at 4°C than at 37°C. Inhibited NK activity recovered partially after incubation for 24 hours.
Keywords
Natural killer activity
Ammonium chloride solution
Descriptions
This work was supported by a Research Grant (No. 544050) from the Ministry of Education, Science and Culture of Japan.
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University School of Medicine
Date of Issued 1983-03
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6863014