Rare Case of a Giant Hamartomous Polyp of Brunner's Gland

During an investigation of the upper digestive tract of a 61-year-old female patient mainly complaining of hematemesis and melena, a peduculated polyp was discovered in the duodenum, and was surgically removed. Histologically, the polyp was recognized as a hamartomous polyp of Brunner's gland. Concerning the cases reported as so-called "Brunner's gland adenoma" it seems that there is a considerable difference in the histo­logical findings between Japanese cases and Western experiences, and this point is discussed in this paper, referring mainly to our case and other cases reported in Japan.