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Hiroshima Journal of Medical Sciences 36 巻 2 号
1987-06 発行
Cellular Immunity of Patients with Lung Cancer and Other Lung Diseases II. Analysis of interleukin-2 production
FUJIWARA Saeko
AKIYAMA Mitoshi
KOBUKE Kyoko
HAKODA Masayuki
YAMADA Michiko
SASAKI Hideo
NERIISHI Kazuo
KOHNO Nobuoki
HOSODA Yutaka
TAKAISHI Masatoshi
YAMAKIDO Michio
Abstract
Interleukin-2 (IL-2) production by stimulated peripheral blood lymphocytes (PBL) from patients with lung cancer and noncancerous respiratory diseases was determined. The results are as follows:
1) Neither sex nor age difference was observed for IL-2 production among healthy people.
2) IL-2 production showed a positive correlation with the Leu-3a/Leu-2a ratio and a negative correlation with the percentage of HLA-DR+ cells.
3) IL-2 production of patients with lung cancer and noncancerous respiratory diseases did not differ from that of healthy persons.
4) No difference in IL-2 production was found in relation to the clinical stage of lung cancer, but subjects with low IL-2 production were mostly observed in the advanced stage group (Stage IV).
1) Neither sex nor age difference was observed for IL-2 production among healthy people.
2) IL-2 production showed a positive correlation with the Leu-3a/Leu-2a ratio and a negative correlation with the percentage of HLA-DR+ cells.
3) IL-2 production of patients with lung cancer and noncancerous respiratory diseases did not differ from that of healthy persons.
4) No difference in IL-2 production was found in relation to the clinical stage of lung cancer, but subjects with low IL-2 production were mostly observed in the advanced stage group (Stage IV).
About This Article
著者キーワード
Lung cancer
Interleukin-2
Other Article
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