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Hiroshima Journal of Medical Sciences Volume 32 Issue 1
published_at 1983-03

Idiopathic Thrombocytopenic Purpura Treated with High Doses of Intravenous Gammaglobulin and Prednisolone : A Case Report

免疫グロブリン大量静注とプレドニソロンとの併用療法を試みた特発性血小板減少性紫斑病の一例
Hamasaki Takashi
Sakano Takashi
Tanaka Yoshito
Fujisawa Kohji
Akatsuka Junichi
Usui Tomofusa
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HiroshimaJMedSci_32_79.pdf
Abstract
We describe a 13-year-old girl with chronic idiopathic thrombocytopenic purpura who showed a response to a high-dose intra venous gammaglobulin combined with prednisolone, without any response to a high-dose intravenous gammaglobulin therapy alone. This observation suggests the additive or multiplicative effects of these two drugs. Platelet-associated IgG level showed an inverse correlation with the number of platelets.
About This Article
Descriptions
This work was supported in part by a grant-in-aid from the Japan Medical Research Foundation and by Scientific Research Grants (project No. 57770632) from the Ministry of Education, Science and Culture of Japan.
Keywords
Idiopathic thrombocytopenic purpnra
High-dose intravenous gammaglobulin
platelet-associated IgG
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