Hiroshima Journal of Medical Sciences Volume 34 Issue 2
published_at 1985-06

Early Onset of Daunomycin Cardiotoxicity in a Case of Acute Myelogeneous Leukemia Associated with Sweet's Syndrome

IMAMURA Nobutaka
MIURA Kazuyuki
KURAMOTO Atsushi
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HiroshimaJMedSci_34_253.pdf
Abstract
A patient of acute leukemia with Sweet's syndrome who developed heart failure after receiving 107 mg/㎡ daunorubicin was reported. There seemed to be genetic factors of individuals in inducing anthracycline cardiotoxicity. Further study on genetic analysis of such a disease will be necessary for clarification of the genetic factors susceptible to anthracyclines.
Descriptions
This work was supported in part by a Grant-in-Aid for Cancer Research from the Ministry of Education, Science and Culture.
Keywords
Daunomycin cardiotoxicity
Sweet's syndrome
Genetic factors