All classes at Hiroshima University were conducted online from the first semester of the 2020 academic year in order to prevent the spread of a new type of corona infection. Even though a team of English teachers provided the same quality and quantity of English classes for students through unsynchronized (on-demand) online classes, it is necessary to verify their effects. Unlike in-person classes, students may not be as motivated to learn English in unsynchronized online classes, as they require individual and autonomous learning. This study compared the results of vocabulary tests of the 2020 Spring semester with those of 2018 and 2019. The vocabulary tests were administered at the beginning and end of each semester, every year, which enabled us to investigate the improvement of vocabulary knowledge during a semester. The results showed that students performed better this year, suggesting that the unsynchronized online classes this year were more effective than in-person classes over the last two years, as far as vocabulary knowledge is concerned. The final section discusses some factors related to the effects of unsynchronized online classes this year, and suggests areas for future research.