The aim of this research was to examine the following relationships in adolescent friendships: social skills (assertive skills and responsive skills), quality of interpersonal interaction (closeness, enjoyment, responsiveness, influence, and confidence), and subjective well-being. The results of the analysis revealed that for people with higher responsive skills and lower responsiveness, the lower the assertive skills, the higher the subjective well-being. By contrast, for people with higher assertive skills and responsive skills, the higher the subjective well-being, the higher the responsiveness of the subjects. In this study, only responsiveness out of the quality in interpersonal interaction was found to affect social skills and subjective well-being, and did not support the hypothesis of being part of all the five qualities of interpersonal interactions.