抗生剤によるビタミンK欠乏性凝固異常のために硬膜外カテーテル抜去に難渋した3症例
麻酔と蘇生 Volume 55 Issue 1
Page 45-47
published_at 2019-03-01
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Title ( jpn ) |
抗生剤によるビタミンK欠乏性凝固異常のために硬膜外カテーテル抜去に難渋した3症例
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Title ( eng ) |
Three Cases Becoming Difficult to Remove Epidural Catheter Postoperatively Due to Coagulation Defect Associated with Antibiotics
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Creator |
Hirata Yuri
Masuda Yoko
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Source Title |
麻酔と蘇生
Ansesthesia and Resuscitation
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Volume | 55 |
Issue | 1 |
Start Page | 45 |
End Page | 47 |
Abstract |
Perioperative vitamin K deficiency can cause severe coagulopathy rapidly. Vitamin K deficiency tends to be overlooked despite the elucidation of pathophysiology and countermeasures. The main causes of vitamin K deficiency are insufficient intake, low supply from intestinal bacteria, and synthesis inhibition of vitamin K by N-methyltetrazolethiol (N - MTT) contained antibiotics. We experienced three cases in which it was difficult to remove epidural catheter because of coagulation abnormality due to vitamin K deficiency after surgery. Vitamin K deficiency should be wary of when epidural catheter is indwelled or withdrawn from a patient who is administered with antibiotic containing N-MTT in the fasted state.
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Keywords |
ビタミンK欠乏症
硬膜外麻酔
抗生剤
NMTT 基
PIVKA-II
vitamin K deficiency
epidural anesthesia
antibiotic
N-methyltetrazolethiol
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NDC |
Medical sciences [ 490 ]
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Language |
jpn
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Resource Type | journal article |
Publisher |
広島麻酔医学会
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Date of Issued | 2019-03-01 |
Publish Type | Version of Record |
Access Rights | open access |
Source Identifier |
[ISSN] 0385-1664
[NCID] AN00232251
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