This paper analyses changes m the employment structure in Middle South Kyushu after 1970, especially in the 1990's. For this purposes, the author uses principal component analysis and cluster analysis. The districts for these analyses are 234 administrative units (shi, cho, son) in Kumamoto, Miyazaki and Kagoshima prefectures. The results are summarized as follows. The employed persons in construction industry have increased in the 1970's and the period of 1991-1996, and decreased in the period of 1996-1999. These changes reflect the movement of the Japanese public investment policy after 1970. The employed persons in manufacturing industry have decreased in 1991-1999 year period. The decrease of the employed persons was remarkable with manufacture of textiles and manufacture of apparel and other finished textile products. The employed persons in these two types of manufacturing sectors decreased markedly in the districts that showed more than 10 percent in the percentage of these manufacturing sectors in 1991. In 1970-1990 year period the employed persons in service industries have increased remarkably in the districts which have a large growth in population. In the 1990's, however, the employed persons in service industries showed a tendency of increasing even in the districts that have a decrease in population. Moreover, the employed persons have increased remarkably in the medical service and the welfare service sector for the elderly in the 1990's.