Bloodstream Infection Caused by Actinomyces neuii subsp. anitratus in a Patient with Breast Cancer: A Case Report and Literature Review

Hiroshima Journal of Medical Sciences 70 巻 2-4 号 43-47 頁 2021-12 発行

アクセス数 : 461 件

ダウンロード数 : 66 件

今月のアクセス数 : 7 件

今月のダウンロード数 : 0 件

この文献の参照には次のURLをご利用ください : https://ir.lib.hiroshima-u.ac.jp/00051924

ファイル情報(添付)	HiroshimaJMedSci_70_43.pdf 4.89 MB 種類 : 全文
タイトル ( eng )	Bloodstream Infection Caused by Actinomyces neuii subsp. anitratus in a Patient with Breast Cancer: A Case Report and Literature Review
作成者	HARA Toshinori KITAGAWA Hiroki KAJIHARA Toshiki KOBA Yumiko TADERA Kayoko NAGAOKA Rie OTA Shiho NAKAOKA Yusuke NOMURA Toshihito OMORI Keitaro SHIGEMOTO Norifumi SASADA Shinsuke OTA Kohei KASHIYAMA Seiya YOKOZAKI Michiya SHIME Nobuaki OHGE Hiroki
収録物名	Hiroshima Journal of Medical Sciences
巻	70
号	2-4
開始ページ	43
終了ページ	47
収録物識別子	[PISSN] 0018-2052 [EISSN] 2433-7668 [NCID] AA00664312
抄録	Actinomyces neuii can grow under aerobic culture conditions and shows a gram-positive rod morphology, similar to that of Corynebacterium spp. A. neuii is usually detected in local pus samples, and published cases of A. neuii bloodstream infections are rare. Here, we report a case of bloodstream infection caused by A. neuii subsp. anitratus. A 53-year-old woman with fever and hypotension was referred to our hospital. The patient underwent surgery for breast cancer and received chemotherapy after central venous (CV) port placement. On day 2, a blood culture in an anaerobic bottle yielded positive results, and A. neuii subsp. anitratus was identified via matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI–TOF MS) and 16S rRNA sequencing. The patient was diagnosed with bloodstream infection caused by A. neuii subsp. anitratus with CV port infection. The CV port was removed and antibiotic treatment resulted in symptom improvement so the patient was discharged on day 28 of hospitalization. MALDI–TOF MS and 16S rRNA sequencing were found to be more useful for the identification of A. neuii than for phenotypic identification. Further research on A. neuii subsp. anitratus infections is required to avoid delayed or missed diagnoses.
著者キーワード	A. neuii subsp. anitratus Gram-positive rods MALDI–TOF MS 16S rRNA sequencing
言語	英語
資源タイプ	紀要論文
出版者	Hiroshima University Medical Press
発行日	2021-12
権利情報	Copyright (c) 2021 Hiroshima University Medical Press
出版タイプ	Version of Record（出版社版。早期公開を含む）
アクセス権	オープンアクセス
収録物識別子	[ISSN] 0018-2052 [ISSN] 2433-7668 [NCID] AA00664312 [DOI] 10.24811/hjms.70.2-4_43 [DOI] https://doi.org/10.24811/hjms.70.2-4_43