Experimental Model of Gastritis Induced by Sodium Taurocholate in Rats

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タイトル ( eng )
Experimental Model of Gastritis Induced by Sodium Taurocholate in Rats
作成者
KISHIMOTO Shinya
OGAWA Mitsuyo
TAKABA Norio
KAMBARA Akihiko
OKAMOTO Kazuma
SHIMIZU Satoru
KUNITA Toshio
DAITOKU Kunihiko
KAJIYAMA Goro
収録物名
Hiroshima Journal of Medical Sciences
35
2
開始ページ 143
終了ページ 147
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
Experimental gastritis was produced in rats by administration of sodium taurocholate (5 mM) for 3 months. The gastritis was associated with mucosal surface injury (erosion), inflammatory cell infiltration and proliferation of interstitial fibrosis in the gastric mucosa. The number of parietal cells per unit area and the mucosal thickness, however, were not different from those in the normal mucosa, indicating that this kind of gastritis was not atrophic but erosive gastritis. The model of erosive gastritis is most useful in studies on gastroprotection and various drugs.
著者キーワード
Gastritis
Taurocholic acid
Erosion
Fibrosis
Parietal cells
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1986-06
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3771272