Detection of Lymphocyte Subsets by Monoclonal Antibodies in Aged and Young Humans

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タイトル ( eng )
Detection of Lymphocyte Subsets by Monoclonal Antibodies in Aged and Young Humans
作成者
YAMAKIDO Michio
YANAGIDA Jitsuro
ISHIOKA Shinichi
MATSUZAKA Shigeru
HOZAWA Soichiro
AKIYAMA Mitoshi
KOBUKE Kyoko
INAMIZU Tsutomu
NISHIMOTO Yukio
収録物名
Hiroshima Journal of Medical Sciences
34
1
開始ページ 87
終了ページ 94
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
With the use of Leu-series monoclonal antibodies, peripheral blood lymphocyte subsets in aged and young humans were determined.
1) In comparison with young individuals, Leu-1+ cells and Leu-2a+ cells were decreased, whereas Leu-7+ cells and Leu-3a/Leu-2a were increased in aged individuals.
2) No sex difference could be observed in lymphocyte subsets.
3) PHA response of lymphocytes showed a negative correlation with Leu-2a+ cells and a positive correlation with Leu-3a/Leu-2a in aged individuals.
著者キーワード
Lymphocyte subset
Monoclonal antibody
Leu series
Aging
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1985-03
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3926724