Detection of Lymphocyte Subsets by Monoclonal Antibodies in Aged and Young Humans
Hiroshima Journal of Medical Sciences Volume 34 Issue 1
Page 87-94
published_at 1985-03
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| File | |
| Title ( eng ) |
Detection of Lymphocyte Subsets by Monoclonal Antibodies in Aged and Young Humans
|
| Creator |
YAMAKIDO Michio
YANAGIDA Jitsuro
ISHIOKA Shinichi
MATSUZAKA Shigeru
HOZAWA Soichiro
AKIYAMA Mitoshi
KOBUKE Kyoko
INAMIZU Tsutomu
NISHIMOTO Yukio
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 34 |
| Issue | 1 |
| Start Page | 87 |
| End Page | 94 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
With the use of Leu-series monoclonal antibodies, peripheral blood lymphocyte subsets in aged and young humans were determined.
1) In comparison with young individuals, Leu-1+ cells and Leu-2a+ cells were decreased, whereas Leu-7+ cells and Leu-3a/Leu-2a were increased in aged individuals. 2) No sex difference could be observed in lymphocyte subsets. 3) PHA response of lymphocytes showed a negative correlation with Leu-2a+ cells and a positive correlation with Leu-3a/Leu-2a in aged individuals. |
| Keywords |
Lymphocyte subset
Monoclonal antibody
Leu series
Aging
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University School of Medicine
|
| Date of Issued | 1985-03 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3926724
|
