Response of Arterial Mechanical Impedance to Different Concentrations of Remifentanil during Abdominal Laparoscopic Colectomy
Hiroshima Journal of Medical Sciences 67 巻 3 号
55-61 頁
2018-09 発行
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種類 :
全文
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タイトル ( eng ) |
Response of Arterial Mechanical Impedance to Different Concentrations of Remifentanil during Abdominal Laparoscopic Colectomy
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作成者 |
Sukhdorj Elbegzaya
Nakamura Ryuji
Yanabe Kensuke
Hirano Hiroki
Hirano Harutoyo
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収録物名 |
Hiroshima Journal of Medical Sciences
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巻 | 67 |
号 | 3 |
開始ページ | 55 |
終了ページ | 61 |
収録物識別子 |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
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抄録 |
A specific and reliable method for monitoring analgesia during general anesthesia is urgently required. Previously, we introduced a method that indicates arterial mechanical properties for estimating arterial wall stiffness (K). However, whether the response of K actually indicates changes in remifentanil target concentrations under continuous surgical stress, is unclear. Thus, we aimed to evaluate how K responds to different remifentanil target concentrations.
This prospective study enrolled 30 patients who underwent laparoscopic colectomy. The patients received 3 different effect-site concentrations (2, 4, and 6 ng/ml) of remifentanil 3 times during the study period. The K values at 4-ng/ml administration were used as control values (Kcontrol). K values at 6-ng/ml administration (K6ng) and those at 2-ng/ml administration (K2ng) were normalized by dividing them by the control values. The results showed that K responded to the changes in remifentanil concentration, significantly decreasing at 6-ng/ml remifentanil effect-site concentration and increasing at 2-ng/ml concentration. The stress response at low analgesia was higher than that at high analgesia, and, as predicted, normalized K2ng was significantly greater than normalized K6ng. In conclusion, we found that K is a sensitive stress response monitor and dynamically responds to changes in remifentanil concentration in invasive stimulation during laparoscopic colectomy. |
著者キーワード |
Photoplethysmogram
Anesthesia
Nociceptive reflex
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NDC分類 |
医学 [ 490 ]
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言語 |
英語
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資源タイプ | 紀要論文 |
出版者 |
Hiroshima University Medical Press
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発行日 | 2018-09 |
権利情報 |
Copyright (c) 2018 Hiroshima University Medical Press
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出版タイプ | Version of Record(出版社版。早期公開を含む) |
アクセス権 | オープンアクセス |
収録物識別子 |
[ISSN] 0018-2052
[ISSN] 2433-7668
[NCID] AA00664312
[DOI] 10.24811/hjms.67.3_55
[DOI] https://doi.org/10.24811/hjms.67.3_55
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