Study of Portal Arterialization with Auxiliary Liver in Rats

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タイトル ( eng )
Study of Portal Arterialization with Auxiliary Liver in Rats
作成者
Hong He-Qun
Asahara Toshimasa
Ito Hisao
Watanabe Hiroshi
Kimura Atsuo
Urushihara Takashi
Marubayashi Seiji
Fukuda Yasuhiko
Nishiki Masayuki
Dohi Kiyohiko
収録物名
Hiroshima Journal of Medical Sciences
40
1
開始ページ 29
終了ページ 33
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
The effect of portal arterialization was examined in 20 heterotopic auxiliary rat livers. Portal blood was supplied from recipient iliac artery (0.58 mm in diameter) connected to the donor portal vein using the cuff technique. Portal hypertension caused by arterial blood pressure resulted in the immediate operative death by bleeding in four of the rats (20%) from the spontaneous rupture of the graft capsule. Severe graft congestion was noticed at autopsy 3-14 days after transplantation in 13 rats. Massive portal and sinusoidal congestion and focal hemorrhagic necrosis were confirmed by pathological examination. The results of our study demonstrate that the portal arterialization used in the auxiliary rat liver transplantation would not be applicable unless the optimal hemodynamic condition is warranted.
著者キーワード
Rat liver
Portal arterialization
Heterotopic auxiliary transplantation
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University Medical Press
発行日 1991-03
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 1864764