Study of Portal Arterialization with Auxiliary Liver in Rats
Hiroshima Journal of Medical Sciences Volume 40 Issue 1
Page 29-33
published_at 1991-03
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| File | |
| Title ( eng ) |
Study of Portal Arterialization with Auxiliary Liver in Rats
|
| Creator |
Hong He-Qun
Asahara Toshimasa
Ito Hisao
Watanabe Hiroshi
Kimura Atsuo
Urushihara Takashi
Marubayashi Seiji
Fukuda Yasuhiko
Nishiki Masayuki
Dohi Kiyohiko
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 40 |
| Issue | 1 |
| Start Page | 29 |
| End Page | 33 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
The effect of portal arterialization was examined in 20 heterotopic auxiliary rat livers. Portal blood was supplied from recipient iliac artery (0.58 mm in diameter) connected to the donor portal vein using the cuff technique. Portal hypertension caused by arterial blood pressure resulted in the immediate operative death by bleeding in four of the rats (20%) from the spontaneous rupture of the graft capsule. Severe graft congestion was noticed at autopsy 3-14 days after transplantation in 13 rats. Massive portal and sinusoidal congestion and focal hemorrhagic necrosis were confirmed by pathological examination. The results of our study demonstrate that the portal arterialization used in the auxiliary rat liver transplantation would not be applicable unless the optimal hemodynamic condition is warranted.
|
| Keywords |
Rat liver
Portal arterialization
Heterotopic auxiliary transplantation
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University Medical Press
|
| Date of Issued | 1991-03 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 1864764
|
