Ammonia Determination as an Early Indicator in Experimental Superior Mesenteric Artery Occlusion
Hiroshima Journal of Medical Sciences 46 巻 4 号
159-167 頁
1997-12 発行
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| ファイル情報(添付) | |
| タイトル ( eng ) |
Ammonia Determination as an Early Indicator in Experimental Superior Mesenteric Artery Occlusion
|
| 作成者 |
Watari Masanobu
Murakami Hironobu
Orihashi Kazumasa
Matsuura Yuichiro
Kajihara Hiroki
|
| 収録物名 |
Hiroshima Journal of Medical Sciences
|
| 巻 | 46 |
| 号 | 4 |
| 開始ページ | 159 |
| 終了ページ | 167 |
| 収録物識別子 |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| 抄録 |
Superior mesenteric artery occlusion (SMAO) is often fatal. An indicator which enables the early diagnosis of SMAO is needed. As we think putrefaction products must appear and increase in the blood and ascites in SMAO, changes in the concentrations of ammonia, one of the putrefaction products, were measured in this study.
Thirteen adult mongrel dogs were used for the in vitro experiment. The jejunum, ileum, and ascending colon were resected and incubated in saline. Changes in ammonia concentrations in the saline were examined at various incubation times. In the in vivo experiment, 11 mongrel dogs comprised the SMAO group and another 10 mongrel dogs comprised the control group. Changes in ammonia concentrations in the blood and ascites were examined in both groups. In the in vitro experiment, ammonia concentrations in the saline bath increased in all samples. It was highest in the sample from around the ascending colon, and lowest from around the jejunum. However, at the end of experiment, this difference became insignificant. In the in vivo experiment, ammonia concentrations in samples of the blood increased early and significantly in the SMAO group, compared with the control group. Ammonia concentrations in samples of the ascites also increased significantly. The in vitro experiment showed that ammonia leaked from the ischemic intestines, and secondarily, a large amount of ammonia was produced from intestinal putrefaction. The in vivo experiment revealed that the ammonia level in the blood could be used as a good early indicator of acute mesenteric ischemia. |
| 著者キーワード |
Ammonia
Putrefaction
Mesenteric ischemia
Superior mesenteric artery occlusion
|
| 内容記述 |
This work was presented at the 96th Annual Meeting of the Japan Society for Surgery, Makuhari, 1996.
|
| NDC分類 |
医学 [ 490 ]
|
| 言語 |
英語
|
| 資源タイプ | 紀要論文 |
| 出版者 |
Hiroshima University Medical Press
|
| 発行日 | 1997-12 |
| 出版タイプ | Version of Record（出版社版。早期公開を含む） |
| アクセス権 | オープンアクセス |
| 収録物識別子 |
[ISSN] 0018-2052
[NCID] AA00664312
|
