Prognostic impact of perineural invasion following pancreatoduodenectomy with lymphadenectomy for ampullary carcinoma
Digestive Diseases and Sciences 53 巻 8 号
2281-2286 頁
2008-08 発行
アクセス数 : 813 件
ダウンロード数 : 191 件
今月のアクセス数 : 3 件
今月のダウンロード数 : 0 件
この文献の参照には次のURLをご利用ください : https://ir.lib.hiroshima-u.ac.jp/00025933
ファイル情報(添付) |
DigDisSci_53_2281.pdf
107 KB
種類 :
全文
|
タイトル ( eng ) |
Prognostic impact of perineural invasion following pancreatoduodenectomy with lymphadenectomy for ampullary carcinoma
|
作成者 |
Uemura Kenichiro
Hayashidani Yasuo
Shimamoto Fumio
|
収録物名 |
Digestive Diseases and Sciences
|
巻 | 53 |
号 | 8 |
開始ページ | 2281 |
終了ページ | 2286 |
抄録 |
Purpose: The aim of this study was to identify prognostic factors in patients undergoing pancreatoduodenectomy with lymphadenectomy for ampullary carcinoma.
Methods: The records of 46 consecutive patients with ampullary carcinoma who underwent pancreatoduodenectomy from 1988 through 2006 were retrospectively reviewed. Results: A 98% rate of potentially curative (R0) resection was achieved. There was no 30-day mortality. Overall 5-year survival rate was 64%.0 Univariate analysis revealed that T3 and T4 tumor (ie, pancreatic parenchymal invasion) (P<0.001), lymph node metastasis (P=0.01), and perineural invasion (P<0.001) were significant predictors of poor prognosis. Furthermore, perineural invasion was found to be a significant independent predictor of poor prognosis by multivariate analysis (P=0.024). Conclusions: Pancreatoduodenectomy with lymphadenectomy for ampullary carcinoma is a safe surgical procedure with an acceptable cure rate. The presence of perineural invasion may be useful for predicting poor prognosis in patients with ampullary carcinoma who undergo potentially curative resection. |
著者キーワード |
ampullary carcinoma
prognostic factor
perineural invasion
pancreatoduodenectomy
|
NDC分類 |
医学 [ 490 ]
|
言語 |
英語
|
資源タイプ | 学術雑誌論文 |
出版者 |
Springer Netherlands
|
発行日 | 2008-08 |
権利情報 |
Copyright (c) 2008 Springer
|
出版タイプ | Author’s Original(十分な品質であるとして、著者から正式な査読に提出される版) |
アクセス権 | オープンアクセス |
収録物識別子 |
The original publication is available at www.springerlink.com
[ISSN] 0163-2116
[DOI] 10.1007/s10620-007-0117-6
[NCID] AA00161107
[DOI] http://dx.doi.org/10.1007/s10620-007-0117-6
|