Phospholipid Molecular Layer that Enhances Distinction of Odors Based on Artificial Sniffing
ACS Sensors 8 巻 12 号
4494-4503 頁
2023-12-07 発行
アクセス数 : 36 件
ダウンロード数 : 18 件
今月のアクセス数 : 6 件
今月のダウンロード数 : 2 件
この文献の参照には次のURLをご利用ください : https://ir.lib.hiroshima-u.ac.jp/00056140
| ファイル情報(添付) | |
| タイトル ( eng ) |
Phospholipid Molecular Layer that Enhances Distinction of Odors Based on Artificial Sniffing
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| 作成者 |
Yotsumoto Mai
Kitahata Hiroyuki
Nakanishi Shinobu
Denda Mitsuhiro
Nagayama Masaharu
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| 収録物名 |
ACS Sensors
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| 巻 | 8 |
| 号 | 12 |
| 開始ページ | 4494 |
| 終了ページ | 4503 |
| 抄録 |
We propose a novel odor-sensing system based on the dynamic response of phospholipid molecular layers for artificial olfaction. Organisms obtain information about their surroundings based on multidimensional information obtained from sniffing, i.e., periodic perturbations. Semiconductor- and receptor-based odor sensors have been developed previously. However, these sensors predominantly identify odors based on one-dimensional information, which limits the type of odor molecule they can identify. Therefore, the development of odor sensors that mimic the olfactory systems of living organisms is useful to overcome this limitation. In this study, we developed a novel odor-sensing system based on the dynamics of phospholipids that responds delicately to chemical substances at room temperature using multidimensional information obtained from periodic perturbations. Odor molecules are periodically supplied to the phospholipid molecular layer as an input sample. The waveform of the surface tension of the phospholipid molecular layer changes depending on the odor molecules and serves as an output. Such characteristic responses originating from the dynamics of odor molecules on the phospholipid molecular layer can be reproduced numerically. The phospholipid molecular layer amplified the information originating from the odor molecule, and the mechanism was evaluated by using surface pressure–area isotherms. This paper offers a platform for an interface-chemistry-based artificial sniffing system as an active sensor and a novel olfactory mechanism via physicochemical responses of the receptor-independent membranes of the organism.
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| 著者キーワード |
Sniffing
Surface Tension
Phospholipid Molecular Layer
Odor-Sensing
Dynamic Response
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| 内容記述 |
This study was supported by JSPS KAKENHI (grant nos. JP20H02712 and JP21H00996), Iketani Science and Technology Foundation (0351181-A), the Cooperative Research Program of “Network Joint Research Center for Materials and Devices” (No. 20231004), to S.N., and the JSPS Bilateral Joint Research Project between Japan and the Polish Academy of Sciences. This study was supported by a Sasakawa Scientific Research Grant from the Japan Science Society to M.Y. (2023-6004).
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| 言語 |
英語
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| 資源タイプ | 学術雑誌論文 |
| 出版者 |
American Chemical Society
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| 発行日 | 2023-12-07 |
| 権利情報 |
This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Sensors, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acssensors.3c00382
This is not the published version. Please cite only the published version.
この論文は出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。
|
| 出版タイプ | Accepted Manuscript（出版雑誌の一論文として受付されたもの。内容とレイアウトは出版社の投稿様式に沿ったもの） |
| アクセス権 | オープンアクセス |
| 収録物識別子 |
[DOI] https://doi.org/10.1021/acssensors.3c00382
～の異版である
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| 助成機関名 |
日本学術振興会
Japan Society for the Promotion of Science
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| 助成機関識別子 |
[Crossref Funder] https://doi.org/10.13039/501100001691
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| 研究課題名 |
時空間発展する自己駆動体の構築
Spatiotemporally developed self-propelled objects
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| 研究課題番号 |
20H02712
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| 助成機関名 |
日本学術振興会
Japan Society for the Promotion of Science
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| 助成機関識別子 |
[Crossref Funder] https://doi.org/10.13039/501100001691
|
| 研究課題名 |
自己駆動体の集団運動に対する数理モデリングと数理解析
自己駆動体の集団運動に対する数理モデリングと数理解析
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| 研究課題番号 |
21H00996
|
