Penicillin Resistance of Pseudomonas aeruginosa Clinical Isolates from Urinary Tract Infections

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タイトル ( eng )
Penicillin Resistance of Pseudomonas aeruginosa Clinical Isolates from Urinary Tract Infections
作成者
SANDA Noriaki
NAKANO Hiroshi
MIYAKE Yoichiro
SUGINAKA Hidekazu
NIHIRA Hiromi
収録物名
Hiroshima Journal of Medical Sciences
35
4
開始ページ 355
終了ページ 362
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
One hundred and thirteen clinical isolates of Pseudomonas aeruginosa from urinary tract infections were tested for their mechanisms of resistance to penicillins. Ninety-eight percent and 100.0% of the strains were resistant (MIC≧100 μg/ml) to ampicillin and penicillin G, respectively, while only 5.3% were resistant to piperacillin. Low permeability of the outer membrane, and penicillinase production were involved in their resistance mechanisms. Peptidoglycan synthesis in ether-treated cells of two representative strains was inhibited by ampicillin and piperacillin at the concentrations markedly lower than that for penicillin G.
著者キーワード
Penicillin
Antibiotic resistance
Urinary tract infection
Pseudomonas aeruginosa
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1986-12
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3106269