Immunoglobulin Production by Peripheral Blood Mononuclear Cells in IgA Nephropathy Patients and their Relatives
Hiroshima Journal of Medical Sciences 35 巻 2 号
177-182 頁
1986-06 発行
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| ファイル情報(添付) | |
| タイトル ( eng ) |
Immunoglobulin Production by Peripheral Blood Mononuclear Cells in IgA Nephropathy Patients and their Relatives
|
| 作成者 |
OKUSHIN Sayuri
TAKAISHI Masatoshi
TAKAHASHI Naoko
OGAWA Takahiko
KANAHARA Koji
HAMAGUCHI Naoki
HIRABAYASHI Akira
WADA Koji
YORIOKA Noriaki
YAMAKIDO Michio
|
| 収録物名 |
Hiroshima Journal of Medical Sciences
|
| 巻 | 35 |
| 号 | 2 |
| 開始ページ | 177 |
| 終了ページ | 182 |
| 収録物識別子 |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| 抄録 |
Immunoglobulin production by peripheral blood mononuclear cells of 27 patients of IgA nephropathy and 11 relatives was determined. In comparison with 15 healthy controls, no significant difference could be observed in both IgA nephropathy patients and relatives of the group not stimulated with PWM, but in the group stimulated with PWM a significant elevation in the production of IgA, IgG and IgM was seen in IgA nephropathy patients, while in the relatives a significant elevation in production of IgA and IgG was observed. It is speculated that immune complexes mainly IgA are the chief cause of development and progression of IgA nephropathy and that IgG and IgM are also involved. In also relatives, the presence of immunological abnormalities similar to those of IgA nephropathy patients is suggested.
|
| 著者キーワード |
IgA nephropathy
Immunoglobulin production
Peripheral blood mononuclear cells
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| NDC分類 |
医学 [ 490 ]
|
| 言語 |
英語
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| 資源タイプ | 紀要論文 |
| 出版者 |
Hiroshima University School of Medicine
|
| 発行日 | 1986-06 |
| 出版タイプ | Version of Record（出版社版。早期公開を含む） |
| アクセス権 | オープンアクセス |
| 収録物識別子 |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3771277
|
