Scirrhous Endocrine Cell Carcinoma of the Stomach with Synchronous Production of Six Polypeptide Hormones and Glycoproteins. A Case Report.

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タイトル ( eng )
Scirrhous Endocrine Cell Carcinoma of the Stomach with Synchronous Production of Six Polypeptide Hormones and Glycoproteins. A Case Report.
作成者
YOKOZAKI Hiroshi
TAHARA Eiichi
収録物名
Hiroshima Journal of Medical Sciences
34
4
開始ページ 381
終了ページ 385
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
A case of scirrhous endocrine cell carcinoma of the stomach in a twenty-nine-yearold man was reported. Histologically, the tumor showing poorly differentiated adenocarcinoma with dense stromal fibrosis, was composed predominantly of tumor cells demonstrating positive argyrophil reaction by Grimelius staining. Immunohistochemically, they revealed the immunoreactivities to gastrin, somatostatin, glucagon, glicentin, pancreatic polypeptide and calcitonin in variable degree. Moreover, synchronous production of carcinoembryonic antigen (CEA), secretory component, lysozyme and mucin were also demonstrated. In view of the multidirectional differentiation, the scirrhous endocrine cell carcinoma might be derived from totipotent stem cell of endodermal origin.
著者キーワード
Endocrine cell carcinoma
Stomach
Peptide hormone
Glycoprotein
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1985-12
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3007399