Scirrhous Endocrine Cell Carcinoma of the Stomach with Synchronous Production of Six Polypeptide Hormones and Glycoproteins. A Case Report.
Hiroshima Journal of Medical Sciences Volume 34 Issue 4
Page 381-385
published_at 1985-12
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| File | |
| Title ( eng ) |
Scirrhous Endocrine Cell Carcinoma of the Stomach with Synchronous Production of Six Polypeptide Hormones and Glycoproteins. A Case Report.
|
| Creator |
YOKOZAKI Hiroshi
TAHARA Eiichi
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 34 |
| Issue | 4 |
| Start Page | 381 |
| End Page | 385 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
A case of scirrhous endocrine cell carcinoma of the stomach in a twenty-nine-yearold man was reported. Histologically, the tumor showing poorly differentiated adenocarcinoma with dense stromal fibrosis, was composed predominantly of tumor cells demonstrating positive argyrophil reaction by Grimelius staining. Immunohistochemically, they revealed the immunoreactivities to gastrin, somatostatin, glucagon, glicentin, pancreatic polypeptide and calcitonin in variable degree. Moreover, synchronous production of carcinoembryonic antigen (CEA), secretory component, lysozyme and mucin were also demonstrated. In view of the multidirectional differentiation, the scirrhous endocrine cell carcinoma might be derived from totipotent stem cell of endodermal origin.
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| Keywords |
Endocrine cell carcinoma
Stomach
Peptide hormone
Glycoprotein
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University School of Medicine
|
| Date of Issued | 1985-12 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3007399
|
