The Influence of Truncal Vagotomy on Acute Gastric Mucosal Lesion in Obstructive Jaundice

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タイトル ( eng )
The Influence of Truncal Vagotomy on Acute Gastric Mucosal Lesion in Obstructive Jaundice
作成者
KODAMA Osamu
TAKEUCHI Hitoshi
ITO Nobuaki
TANAKA Tsuneo
SEIKOH Rokuro
ICHIBA Yasuyuki
DOHI Kiyohiko
収録物名
Hiroshima Journal of Medical Sciences
34
3
開始ページ 347
終了ページ 350
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
With a view to examining the influence of truncal vagotomy on acute gastric mucosal lesion (AGML) in obstructive jaundice, the authors prepared the non-vagotomized group and the vagotomized group of rats with obstructive jaundice. Further, cold restraint stress was loaded on the two groups for 30 min, and the following results were obtained:
1) The incidence of AGML in the vagotomized group before stress was inhibited to 17% in both the 3-week group and 4-week group, as compared to 33-38% in the non-vagotomized group. The incidence of AGML in the vagotomized group after stress was inhibited to 17% in the 3-week group and 33% in the 4-week group, as compared to 78% in the non-vagotomized group.
2) Gastric mucosal histamine (HA) contents in the vagotomized group before stress in both the 3-week group and the 4-week group were significantly increased (p < 0.05) as compared with the levels in the non-vagotomized group. As concerns gastric mucosal serotonin (5-HT) contents, however, no significant difference was noted between both groups. The contents of both amines in the gastric mucosa in the non-vagotomized group, a significant decrease (p < 0.05) was observed in both the 3-week group and 4-week group after stress, while in the vagotomized group no significant changes were found.
著者キーワード
Obstructive jaundice
AGML
Truncal vagotomy
Amine
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1985-09
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 4066401