Adherence of Protease-Deficient Mutants of Pseudomonas aeruginosa to a Rabbit Cornea Cell Line (SIRC) Cells
Hiroshima Journal of Medical Sciences 34 巻 1 号
113-117 頁
1985-03 発行
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| ファイル情報(添付) | |
| タイトル ( eng ) |
Adherence of Protease-Deficient Mutants of Pseudomonas aeruginosa to a Rabbit Cornea Cell Line (SIRC) Cells
|
| 作成者 |
IIDA Takashi
KATOH Masafumi
MATSUO Yoshiyasu
|
| 収録物名 |
Hiroshima Journal of Medical Sciences
|
| 巻 | 34 |
| 号 | 1 |
| 開始ページ | 113 |
| 終了ページ | 117 |
| 収録物識別子 |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| 抄録 |
Seven protease-deficient mutants were isolated from Pseudomonas aeruginosa strain IFO 3455 which was mutagenized with nitrosoguanidine. Characterization of these mutants in vitro revealed that all mutants showed pleiotropic changes in the production of other extracellular substances. Among the mutants, two were chosen for a bacterial adherence test to Rabbit Cornea Cell Line (SIRC) cells. One mutant (IFO 3455-2) completely lost its protease activity. Another (IFO 3455-3) retained a low protease activity and was relatively similar to the parental strain with respect to extracellular products except for protease. Both mutants gave not a marked but a slight decrease of adherence as compared with the parental strain. This finding suggests that besides protease more factors are involved in the adhesion between P. aeruginosa and SIRC cells.
|
| 著者キーワード |
P. aeruginosa
Mutant
Protease
Adherence
SIRC cell
|
| NDC分類 |
医学 [ 490 ]
|
| 言語 |
英語
|
| 資源タイプ | 紀要論文 |
| 出版者 |
Hiroshima University School of Medicine
|
| 発行日 | 1985-03 |
| 出版タイプ | Version of Record（出版社版。早期公開を含む） |
| アクセス権 | オープンアクセス |
| 収録物識別子 |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3926722
|
