CHEMISTRY OF ANTI-HIV ACTIVE TRIMERIC PYRANONAPHTHO-QUINONE CONOCURVONE: SYNTHETIC STUDIES TOWARDS MONOMERIC TERETIFOLIONE B AND RELATED COMPOUNDS

Heterocycles 100 巻 2 号 177-193 頁 2019-12-23 発行
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タイトル ( eng )
CHEMISTRY OF ANTI-HIV ACTIVE TRIMERIC PYRANONAPHTHO-QUINONE CONOCURVONE: SYNTHETIC STUDIES TOWARDS MONOMERIC TERETIFOLIONE B AND RELATED COMPOUNDS
作成者
Katakawa Kazuaki
収録物名
Heterocycles
100
2
開始ページ 177
終了ページ 193
抄録
Pyranonaphthoquinone natural products are widely distributed in plants and microorganisms and have diverse biological activities. Angular benzochromenes are a small class of natural products isolated from Conospermum and Pentas plants. Of these, conocurvone was isolated from Conospermum as a trimeric pyranonaphthoquinone that has potent anti-HIV activity. We have focused on the total synthesis of compounds that exhibit biological activity or whose activity is enhanced upon oligomerization. This review describes the discovery and biological activities of the trimeric pyranonaphthoquinone conocurvone and related compounds, as well as our and other researchers’ synthetic studies toward monomeric pyranonaphthoquinones.
内容記述
This work was partially supported by The Uehara Memorial Foundation, a Grant from Musashino Joshi-Gakuin, and JSPS KAKENHI Grant Number JP19K06975.
言語
英語
資源タイプ 学術雑誌論文
出版者
The Japan Institute of Heterocyclic Chemistry
発行日 2019-12-23
権利情報
Copyright (c) 2019 The Japan Institute of Heterocyclic Chemistry
This is the uncorrected proof, and is not the published version. Please cite only the published version. この論文は著者校正前原稿であり、出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 1881-0942
[DOI] 10.3987/REV-19-915
[DOI] https://doi.org/10.3987/REV-19-915