CHEMISTRY OF ANTI-HIV ACTIVE TRIMERIC PYRANONAPHTHO-QUINONE CONOCURVONE: SYNTHETIC STUDIES TOWARDS MONOMERIC TERETIFOLIONE B AND RELATED COMPOUNDS
Heterocycles Volume 100 Issue 2
Page 177-193
published_at 2019-12-23
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| File | |
| Title ( eng ) |
CHEMISTRY OF ANTI-HIV ACTIVE TRIMERIC PYRANONAPHTHO-QUINONE CONOCURVONE: SYNTHETIC STUDIES TOWARDS MONOMERIC TERETIFOLIONE B AND RELATED COMPOUNDS
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| Creator |
Katakawa Kazuaki
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| Source Title |
Heterocycles
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| Volume | 100 |
| Issue | 2 |
| Start Page | 177 |
| End Page | 193 |
| Abstract |
Pyranonaphthoquinone natural products are widely distributed in plants and microorganisms and have diverse biological activities. Angular benzochromenes are a small class of natural products isolated from Conospermum and Pentas plants. Of these, conocurvone was isolated from Conospermum as a trimeric pyranonaphthoquinone that has potent anti-HIV activity. We have focused on the total synthesis of compounds that exhibit biological activity or whose activity is enhanced upon oligomerization. This review describes the discovery and biological activities of the trimeric pyranonaphthoquinone conocurvone and related compounds, as well as our and other researchers’ synthetic studies toward monomeric pyranonaphthoquinones.
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| Descriptions |
This work was partially supported by The Uehara Memorial Foundation, a Grant from Musashino Joshi-Gakuin, and JSPS KAKENHI Grant Number JP19K06975.
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| Language |
eng
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| Resource Type | journal article |
| Publisher |
The Japan Institute of Heterocyclic Chemistry
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| Date of Issued | 2019-12-23 |
| Rights |
Copyright (c) 2019 The Japan Institute of Heterocyclic Chemistry
This is the uncorrected proof, and is not the published version. Please cite only the published version. この論文は著者校正前原稿であり、出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。
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| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 1881-0942
[DOI] 10.3987/REV-19-915
[DOI] https://doi.org/10.3987/REV-19-915
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