Solitary Cranial Langerhans Cell Histiocytosis : Two case reports
Hiroshima Journal of Medical Sciences 64 巻 4 号
59-63 頁
2015-12 発行
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| ファイル情報(添付) | |
| タイトル ( eng ) |
Solitary Cranial Langerhans Cell Histiocytosis : Two case reports
|
| 作成者 |
Karki Prasanna
Hirano Hirofumi
Yamahata Hitoshi
Fujio Shingo
Yonezawa Hajime
Bohara Manoj
Oyoshi Tatsuki
Hanaya Ryosuke
Arita Kazunori
|
| 収録物名 |
Hiroshima Journal of Medical Sciences
|
| 巻 | 64 |
| 号 | 4 |
| 開始ページ | 59 |
| 終了ページ | 63 |
| 収録物識別子 |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| 抄録 |
Langerhans cell histiocytosis (LCH) is a proliferation of Langerhans cells intermixed with inflammatory cells, in particular eosinophils, that may manifest as a unisystem (unifocal or multifocal) or multisystem disease. We describe the clinical and histologic spectrum of LCH of the orbit and skull in our two cases. Both cases had unifocal erosive skull lesions with a history of trauma. Typical histologic features included numerous histiocytes with varying degrees of giant cell formation and scattered eosinophilic granulocytes. The presence of Langerhans cells was confirmed by CD1a and S100 immunohistochemistry. LCH has an excellent prognosis when treated with surgical resection, steroids and radiotherapy or chemotherapy. One of our patients is disease free at 7 year follow-up and one patient had regression of lesion on follow-up.
|
| 著者キーワード |
Langerhans cell histiocytosis
Skull
Immunostaining
Histology
|
| NDC分類 |
医学 [ 490 ]
|
| 言語 |
英語
|
| 資源タイプ | 紀要論文 |
| 出版者 |
Hiroshima University Medical Press
|
| 発行日 | 2015-12 |
| 権利情報 |
Hiroshima University Medical Press
|
| 出版タイプ | Version of Record（出版社版。早期公開を含む） |
| アクセス権 | オープンアクセス |
| 収録物識別子 |
[ISSN] 0018-2052
[NCID] AA00664312
|
