On the Study of Developmental Genetics of Isolated Pulmonary Hypoplasia

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タイトル ( eng )
On the Study of Developmental Genetics of Isolated Pulmonary Hypoplasia
タイトル ( jpn )
肺動脈発育不全に関する発生遺伝学的研究
作成者
Satow Yukio
Okamoto Naomasa
Yi Lee Juing
Sumida Hiroshi
収録物名
Hiroshima Journal of Medical Sciences
31
2
開始ページ 97
終了ページ 102
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
We have carried out the study on the heart anomalies of the DHS mice and Pdn mice fetuses and newborns which are known to produce genetically induced polydactyly. The results have revealed that the heart anomalies are mainly isolated hypoplasia of the pulmonary artery and that these anomalies are not always associated with polydactyly. The isolated hypoplasia of the pulmonary artery show a tendency to develop among uterine sibilings. These might suggest that the genetic traits of heart anomalies are controlled by the polygenic or multifactorial inheritances.
著者キーワード
DHS mice
Pdn mice
Polydactyly
Pulmonary hypoplasia
Polygene
内容記述
This study has been supported in part by Research Grants from Japanese Ministry of Education on the Experimental study of the morphogenesis of cardiovascular anomaly (448140), and on the Fine structure and pathogenesis of the heart and vessel (511102, Research Director: Professor Naomasa OKAMOTO).
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1982-06-10
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 7129955