On the Study of Developmental Genetics of Isolated Pulmonary Hypoplasia
Hiroshima Journal of Medical Sciences Volume 31 Issue 2
Page 97-102
published_at 1982-06-10
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| File | |
| Title ( eng ) |
On the Study of Developmental Genetics of Isolated Pulmonary Hypoplasia
|
| Title ( jpn ) |
肺動脈発育不全に関する発生遺伝学的研究
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| Creator |
Satow Yukio
Okamoto Naomasa
Yi Lee Juing
Sumida Hiroshi
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| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 31 |
| Issue | 2 |
| Start Page | 97 |
| End Page | 102 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
We have carried out the study on the heart anomalies of the DHS mice and Pdn mice fetuses and newborns which are known to produce genetically induced polydactyly. The results have revealed that the heart anomalies are mainly isolated hypoplasia of the pulmonary artery and that these anomalies are not always associated with polydactyly. The isolated hypoplasia of the pulmonary artery show a tendency to develop among uterine sibilings. These might suggest that the genetic traits of heart anomalies are controlled by the polygenic or multifactorial inheritances.
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| Keywords |
DHS mice
Pdn mice
Polydactyly
Pulmonary hypoplasia
Polygene
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| Descriptions |
This study has been supported in part by Research Grants from Japanese Ministry of Education on the Experimental study of the morphogenesis of cardiovascular anomaly (448140), and on the Fine structure and pathogenesis of the heart and vessel (511102, Research Director: Professor Naomasa OKAMOTO).
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| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University School of Medicine
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| Date of Issued | 1982-06-10 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 7129955
|
