Purification of Thiol Protease Inhibitor from Human Lung Cancer Tissue

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タイトル ( eng )
Purification of Thiol Protease Inhibitor from Human Lung Cancer Tissue
タイトル ( jpn )
ヒト肺癌組織からのチオールプロテアーゼインヒビターの精製
作成者
Okumichi Tsuneo
Nishiki Masayuki
Takasugi Sumiyoshi
Yamane Motoi
Ezaki Haruo
収録物名
Hiroshima Journal of Medical Sciences
33
4
開始ページ 801
終了ページ 808
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
It was confirmed that the thiol protease inhibitory activities in human lung cancer extracts were significantly higher than normal lung tissue extracts.

Furthermore the thiol protease inhibitor was extracted from human lung cancer tissue and purified by papain-Sepharose and Sephadex G-100 column chromatographies. The purified inhibitor inhibited papain and ficin, and its molecular weight determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis was about 13,000.
著者キーワード
Thiol protease inhibitor
Human lung cancer
内容記述
This research was funded in part by Grant-in-Aid for Scientific Research, Project 56480213, of the Japanese Ministry of Education.
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1984-12
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6398816